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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: BLM All Species: 11.52
Human Site: S175 Identified Species: 19.49
UniProt: P54132 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54132 NP_000048.1 1417 159000 S175 S F V T P P Q S H F V R V S T
Chimpanzee Pan troglodytes XP_510594 1417 158822 S175 S F V T P P Q S H F V R V S T
Rhesus Macaque Macaca mulatta XP_001097543 1416 158885 S175 A F V T P P Q S H F V R V S T
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O88700 1416 158347 R175 L A K N P A T R V S T A Q K M
Rat Rattus norvegicus Q6AYJ1 621 69624
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515695 791 89186
Chicken Gallus gallus Q9I920 1142 126164
Frog Xenopus laevis Q9DEY9 1364 152305 G164 K S H A G K G G K T P Q K C K
Zebra Danio Brachydanio rerio XP_701357 1261 139417 S97 V N F F T A P S K P K T N T V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VGI8 1487 166060 S258 S P A N P L V S N N L A S I S
Honey Bee Apis mellifera XP_396209 961 109321
Nematode Worm Caenorhab. elegans O18017 988 110641
Sea Urchin Strong. purpuratus XP_001175892 1394 152920 R185 P P A T K S S R T P N K K P L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P35187 1447 163819 N172 S I G K Q L E N D I K L E V I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.1 N.A. N.A. 76.9 21.2 N.A. 46.3 47.9 50.8 41.6 N.A. 27.8 30.9 26.5 31.5
Protein Similarity: 100 99.2 97.7 N.A. N.A. 85.2 30.9 N.A. 50.1 60.7 66.6 54 N.A. 47 47.1 40.2 47.6
P-Site Identity: 100 100 93.3 N.A. N.A. 6.6 0 N.A. 0 0 0 6.6 N.A. 20 0 0 6.6
P-Site Similarity: 100 100 100 N.A. N.A. 6.6 0 N.A. 0 0 6.6 13.3 N.A. 40 0 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 44.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 15 8 0 15 0 0 0 0 0 15 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 8 0 0 0 0 0 8 0 0 % E
% Phe: 0 22 8 8 0 0 0 0 0 22 0 0 0 0 0 % F
% Gly: 0 0 8 0 8 0 8 8 0 0 0 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 22 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 8 0 0 0 8 8 % I
% Lys: 8 0 8 8 8 8 0 0 15 0 15 8 15 8 8 % K
% Leu: 8 0 0 0 0 15 0 0 0 0 8 8 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 8 0 15 0 0 0 8 8 8 8 0 8 0 0 % N
% Pro: 8 15 0 0 36 22 8 0 0 15 8 0 0 8 0 % P
% Gln: 0 0 0 0 8 0 22 0 0 0 0 8 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 15 0 0 0 22 0 0 0 % R
% Ser: 29 8 0 0 0 8 8 36 0 8 0 0 8 22 8 % S
% Thr: 0 0 0 29 8 0 8 0 8 8 8 8 0 8 22 % T
% Val: 8 0 22 0 0 0 8 0 8 0 22 0 22 8 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _